HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Methyl-alpha-(2-methylpropyl)-1,2,4-oxadiazole-3-methanamine → 6-Cyclopropylmethoxy-5-(3,3-difluoro-azetidin-1-yl)-pyridine-2-carboxylic acid [3-methyl-1-(5-methyl-[1,2,4]oxadiazol-3-yl)-butyl]-amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Methyl-alpha-(2-methylpropyl)-1,2,4-oxadiazole-3-methanamine | HCID 43559329 | — |
| Reactant | 6-(Cyclopropylmethoxy)-5-(3,3-difluoroazetidin-1-yl)picolinic acid | HCID 71087292 | — |
| Product | 6-Cyclopropylmethoxy-5-(3,3-difluoro-azetidin-1-yl)-pyridine-2-carboxylic acid [3-methyl-1-(5-methyl-[1,2,4]oxadiazol-3-yl)-butyl]-amide | HCID 71114538 | — |
Reaction Steps
The title compound was synthesized in analogy to Example 1, using 6-cyclopropylmethoxy-5-(3,3-difluoro-azetidin-1-yl)-pyridine-2-carboxylic acid (Example 69 b) and 5-methyl-α-(2-methylpropyl)-1,2,4-oxadiazole-3-methanamine (CAN 1155538-06-9) as starting materials. MS (EI): m/e=436.0 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09290451B2 |
| Source dataset | uspto-grants-2016_03 |
| ORD ID | ord-c3642b34547141fa8edb2019fd64292a |
| Source note | uspto-grants-2016_03 |