HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Bromo-6-(2,2,2-trifluoro-ethoxy)-pyridine-2-carboxylic acid → 5-Bromo-6-(2,2,2-trifluoro-ethoxy)-pyridine-2-carboxylic acid (3-thiazol-2-yl-oxetan-3-yl)-amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Bromo-6-(2,2,2-trifluoro-ethoxy)-pyridine-2-carboxylic acid | HCID 71087450 | — |
| Reactant | 3-(1,3-Thiazol-2-yl)oxetan-3-amine hydrochloride | HCID 86674782 | — |
| Product | 5-Bromo-6-(2,2,2-trifluoro-ethoxy)-pyridine-2-carboxylic acid (3-thiazol-2-yl-oxetan-3-yl)-amide | HCID 71113182 | — |
Reaction Steps
The title compound was synthesized in analogy to Example 280c, using 5-bromo-6-(2,2,2-trifluoro-ethoxy)-pyridine-2-carboxylic acid (Example 282a) and 3-(thiazol-2-yl)oxetan-3-amine hydrochloride (Example 281b) as starting materials, MS (EI): m/e=438.0 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09290451B2 |
| Source dataset | uspto-grants-2016_03 |
| ORD ID | ord-218e481dc86f4be798e261d0d48286a3 |
| Source note | uspto-grants-2016_03 |