Cyclopropanemethanamine → HCID 71105688, compound

HRID 927729Notes

Reaction equation

HRID 927729 reaction equation
[CH:1]1([C:4]2[CH:5]=[CH:6][C:7]([C:15]([NH:17][C:18]([CH2:24][CH3:25])([CH2:22][CH3:23])[C:19](O)=[O:20])=[O:16])=[N:8][C:9]=2[O:10][CH2:11][CH:12]2[CH2:14][CH2:13]2)[CH2:3][CH2:2]1.[CH:26]1([CH2:29][NH2:30])[CH2:28][CH2:27]1>>[CH:26]1([CH2:29][NH:30][C:19]([C:18]([NH:17][C:15]([C:7]2[CH:6]=[CH:5][C:4]([CH:1]3[CH2:2][CH2:3]3)=[C:9]([O:10][CH2:11][CH:12]3[CH2:13][CH2:14]3)[N:8]=2)=[O:16])([CH2:22][CH3:23])[CH2:24][CH3:25])=[O:20])[CH2:28][CH2:27]1

Participants

3

Reactant 2

HCID 75646CyclopropanemethanamineHCID 710875422-(5-Cyclopropyl-6-(cyclopropylmethoxy)picolinamido)-2-ethylbutanoic acid

Product 1

HCID 71105688HCID 71105688, compound

Procedure

The title compound was synthesized in analogy to Example 1, using 2-(5-cyclopropyl-6-(cyclopropylmethoxy)picolinamido)-2-ethylbutanoic acid (Example 274 a) and cyclopropylmethanamine (CAN 2516-47-4) as starting materials. MS (EI): m/e=400.1 [M+H]+.

Sources & evidence

ORD record
ord-4fc05fa0812a4cf492d9f9decfbd50c7
Source dataset
uspto-grants-2016_03
Patent number
US09290451B2

Reaction notes

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