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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 927730Generated: October 30, 2026

2-(2-Pyridyl)-2-propylamine → 5-Cyclopropyl-6-cyclopropylmethoxy-pyridine-2-carboxylic acid (1-methyl-1-pyridin-2-yl-ethyl)-amide

https://huagongshe.com/reaction/927730

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(2-Pyridyl)-2-propylamineHCID 22736922—
Reactant5-Cyclopropyl-6-cyclopropylmethoxy-pyridine-2-carboxylic acidHCID 71087346—
Product5-Cyclopropyl-6-cyclopropylmethoxy-pyridine-2-carboxylic acid (1-methyl-1-pyridin-2-yl-ethyl)-amideHCID 71093589—

Reaction Steps

The title compound was synthesized in analogy to Example 1, using 5-cyclopropyl-6-cyclopropylmethyloxy-pyridine-2-carboxylic acid (Example 42a) and α,α-dimethyl-2-pyridinemethanamine (CAN 52568-28-2) as starting materials, LC-MS (UV peak area/ESI) 100%, 352.2021 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09290451B2
Source datasetuspto-grants-2016_03
ORD IDord-46167100dc8044d9a31a5587d83c973f
Source noteuspto-grants-2016_03