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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 927736생성일: 2026년 10월 25일

4-Amino-1-methyl-2-pyrrolidinone hydrochloride → 6-Cyclopropylmethoxy-5-(3,3-difluoro-azetidin-1-yl)-pyridine-2-carboxylic acid (1-methyl-5-oxo-pyrrolidin-3-yl)-amide

https://huagongshe.com/reaction/927736

반응식

참여 물질

역할이름HCID투입량
반응물4-Amino-1-methyl-2-pyrrolidinone hydrochlorideHCID 50988498—
반응물6-(Cyclopropylmethoxy)-5-(3,3-difluoroazetidin-1-yl)picolinic acidHCID 71087292—
생성물6-Cyclopropylmethoxy-5-(3,3-difluoro-azetidin-1-yl)-pyridine-2-carboxylic acid (1-methyl-5-oxo-pyrrolidin-3-yl)-amideHCID 71105693—

반응 단계

The title compound was synthesized in analogy to Example 1, using 6-cyclopropylmethoxy-5-(3,3-difluoro-azetidin-1-yl)-pyridine-2-carboxylic acid (Example 69 b) and 4-amino-1-methylpyrrolidin-2-one hydrochloride (CAN 1228838-07-0) as starting materials. MS (EI): m/e=381.3 [M+H]+.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US09290451B2
출처 데이터셋uspto-grants-2016_03
ORD IDord-1e096169d66849c690fcca1d596d165c
출처 메모uspto-grants-2016_03