HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Methyl-1-(pyridin-2-yl)butan-1-amine → 6-Cyclopropylmethoxy-5-(3,3-difluoro-azetidin-1-yl)-pyridine-2-carboxylic acid (3-methyl-1-pyridin-2-yl-butyl)-amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Methyl-1-(pyridin-2-yl)butan-1-amine | HCID 60818623 | — |
| Reactant | 6-(Cyclopropylmethoxy)-5-(3,3-difluoroazetidin-1-yl)picolinic acid | HCID 71087292 | — |
| Product | 6-Cyclopropylmethoxy-5-(3,3-difluoro-azetidin-1-yl)-pyridine-2-carboxylic acid (3-methyl-1-pyridin-2-yl-butyl)-amide | HCID 71105701 | — |
Reaction Steps
In analogy to the procedure described in Example 293, 6-(cyclopropylmethoxy)-5-(3,3-difluoroazetidin-1-yl)picolinic acid (Example 69 b) and 3-methyl-1-(pyridin-2-yl)butan-1-amine (CAN 825647-69-6) were condensed to the title product. MS (EI): m/e=431.4 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09290451B2 |
| Source dataset | uspto-grants-2016_03 |
| ORD ID | ord-de8ce35f489b420282207ab741f3e1c9 |
| Source note | uspto-grants-2016_03 |