HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
6-(Cyclopropylmethoxy)-5-(3,3-difluoroazetidin-1-yl)picolinic acid → 6-Cyclopropylmethoxy-5-(3,3-difluoro-azetidin-1-yl)-pyridine-2-carboxylic acid (3-methyl-1-pyridazin-3-yl-butyl)-amide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 6-(Cyclopropylmethoxy)-5-(3,3-difluoroazetidin-1-yl)picolinic acid | HCID 71087292 | — |
| Edukt | 3-Methyl-1-(pyridazin-3-yl)butan-1-amine | HCID 86674794 | — |
| Produkt | 6-Cyclopropylmethoxy-5-(3,3-difluoro-azetidin-1-yl)-pyridine-2-carboxylic acid (3-methyl-1-pyridazin-3-yl-butyl)-amide | HCID 71105703 | — |
Reaktionsschritte
In analogy to the procedure described in Example 293, 6-(cyclopropylmethoxy)-5-(3,3-difluoroazetidin-1-yl)picolinic acid (Example 69 b) and 3-methyl-1-(pyridazin-3-yl)butan-1-amine were condensed to the title product. MS (EI): m/e=432.4 [M+H]+.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US09290451B2 |
| Quelldatensatz | uspto-grants-2016_03 |
| ORD ID | ord-bfde5aea5bd64f04bfb42b4b26bc3044 |
| Quellennotiz | uspto-grants-2016_03 |