Leucinamide → HCID 71105714, compound

HRID 927787Notes

Reaction equation

[CH2:1]([S:5][C:6]1[N:11]=[C:10]([C:12]([OH:14])=O)[CH:9]=[CH:8][CH:7]=1)[CH:2]([CH3:4])[CH3:3].[NH2:15][C@@H:16]([CH2:20][CH:21]([CH3:23])[CH3:22])[C:17]([NH2:19])=[O:18]>>[C:17]([C@@H:16]([NH:15][C:12]([C:10]1[CH:9]=[CH:8][CH:7]=[C:6]([S:5][CH2:1][CH:2]([CH3:3])[CH3:4])[N:11]=1)=[O:14])[CH2:20][CH:21]([CH3:23])[CH3:22])(=[O:18])[NH2:19]

Participants

Reactant 2

HCID 69640Leucinamide

HCID 60645478HCID 60645478, compound

Product 1

HCID 71105714HCID 71105714, compound

Procedure

The title compound was synthesized in analogy to Example 1, using 6-(isobutylthio)picolinic acid (CAN 1247607-03-9) and (2S)-2-amino-4-methyl-pentanamide (CAN 687-51-4) as starting materials. MS (EI): m/e=324.2 [M+H]+.

Sources & evidence

ORD record: ord-3d26c84c5e344ffaa1c19c85e737a384
Source dataset: uspto-grants-2016_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US09290451B2

Reaction notes

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