HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl 2-amino-2-ethylbutanoate hydrochloride → Ethyl 2-(5-cyclopropyl-6-(4-fluorobenzyl)picolinamido)-2-ethylbutanoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl 2-amino-2-ethylbutanoate hydrochloride | HCID 24201639 | — |
| Reactant | 5-Cyclopropyl-6-(4-fluoro-benzyl)-pyridine-2-carboxylic acid | HCID 71087698 | — |
| Product | Ethyl 2-(5-cyclopropyl-6-(4-fluorobenzyl)picolinamido)-2-ethylbutanoate | HCID 71087869 | — |
Reaction Steps
The title compound was synthesized in analogy to Example 1, using 5-cyclopropyl-6-(4-fluoro-benzyl)-pyridine-2-carboxylic acid (Example 155 g) and ethyl 2-amino-2-ethylbutanoate hydrochloride (CAN 1135219-29-2) as starting materials. MS (EI): m/e=413.1 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09290451B2 |
| Source dataset | uspto-grants-2016_03 |
| ORD ID | ord-85e6f6ea50e84c06aa230a525118ae8b |
| Source note | uspto-grants-2016_03 |