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Sodium Hydroxide → 2-{[5-Cyclopropyl-6-(4-fluoro-benzyl)-pyridine-2-carbonyl]-amino}-2-ethyl-butyric acid
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Sodium Hydroxide | HCID 14798 | — |
| 反応物 | Ethyl 2-(5-cyclopropyl-6-(4-fluorobenzyl)picolinamido)-2-ethylbutanoate | HCID 71087869 | — |
| 生成物 | 2-{[5-Cyclopropyl-6-(4-fluoro-benzyl)-pyridine-2-carbonyl]-amino}-2-ethyl-butyric acid | HCID 71087929 | — |
反応手順
In analogy to the procedure described in Example 252 b), ethyl 2-(5-cyclopropyl-6-(4-fluorobenzyl)picolinamido)-2-ethylbutanoate was treated with sodium hydroxide to give the title compound as white solid. MS: 383.3 [M−H]−.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US09290451B2 |
| 出典データセット | uspto-grants-2016_03 |
| ORD ID | ord-097df94c99b844ceb0bf75ab8ca6b22a |
| 出典メモ | uspto-grants-2016_03 |