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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 927814Generated: October 26, 2026

4-Methanesulfonyl-2-methylbutan-2-amine → 5-Cyclopropyl-6-cyclopropylmethoxy-pyridine-2-carboxylic acid (3-methanesulfonyl-1,1-dimethyl-propyl)-amide

https://huagongshe.com/reaction/927814

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Methanesulfonyl-2-methylbutan-2-amineHCID 54595866—
Reactant5-Cyclopropyl-6-cyclopropylmethoxy-pyridine-2-carboxylic acidHCID 71087346—
Product5-Cyclopropyl-6-cyclopropylmethoxy-pyridine-2-carboxylic acid (3-methanesulfonyl-1,1-dimethyl-propyl)-amideHCID 71105733—

Reaction Steps

The title compound was synthesized in analogy to Example 1, using 5-cyclopropyl-6-cyclopropylmethyloxy-pyridine-2-carboxylic acid (Example 42a) and 2-methyl-4-(methylsulfonyl)-2-butanamine (CAN 1250515-16-2) as starting materials; LC-MS (UV peak area/ESI) 95%, 381.1843 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09290451B2
Source datasetuspto-grants-2016_03
ORD IDord-2e00b6d28d4e454b97f4fd8167be068f
Source noteuspto-grants-2016_03