HuagongsheHuagongshe Chemistry Print Report · For research reference only
(2S)-2-amino-N,4,4-trimethyl-pentanamide → 5-Cyclopropyl-6-(2-methyl-propane-1-sulfonyl)-pyridine-2-carboxylic acid ((S)-3,3-dimethyl-1-methylcarbamoyl-butyl)-amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (2S)-2-amino-N,4,4-trimethyl-pentanamide | HCID 57635521 | — |
| Reactant | 5-Cyclopropyl-6-(isobutylsulfonyl)picolinic acid | HCID 71087731 | — |
| Product | 5-Cyclopropyl-6-(2-methyl-propane-1-sulfonyl)-pyridine-2-carboxylic acid ((S)-3,3-dimethyl-1-methylcarbamoyl-butyl)-amide | HCID 71105749 | — |
Reaction Steps
The title compound was synthesized in analogy to Example 1, using 5-cyclopropyl-6-(isobutylsulfonyl)picolinic acid (Example 351 b) and (2S)-2-amino-N,4,4-trimethyl-pentanamide (CAN 1160161-70-5) as starting materials. MS (EI): m/e=424.6 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09290451B2 |
| Source dataset | uspto-grants-2016_03 |
| ORD ID | ord-c212850a4b014bd586b8286a1bec2b1a |
| Source note | uspto-grants-2016_03 |