HCID 55271418, compound → HCID 71087581, compound

HRID 927828Notes

Reaction equation

HRID 927828 reaction equation
[CH:1]1([C:4]2[CH:5]=[CH:6][C:7]([C:15]([OH:17])=O)=[N:8][C:9]=2[O:10][CH2:11][CH:12]2[CH2:14][CH2:13]2)[CH2:3][CH2:2]1.[CH3:18][C:19]([O:22][C:23]([N:25]([CH2:27][CH:28]1[CH2:30][CH2:29]1)[NH2:26])=[O:24])([CH3:21])[CH3:20]>>[C:19]([O:22][C:23]([N:25]([CH2:27][CH:28]1[CH2:29][CH2:30]1)[NH:26][C:15]([C:7]1[CH:6]=[CH:5][C:4]([CH:1]2[CH2:2][CH2:3]2)=[C:9]([O:10][CH2:11][CH:12]2[CH2:13][CH2:14]2)[N:8]=1)=[O:17])=[O:24])([CH3:21])([CH3:18])[CH3:20]

Participants

3

Reactant 2

HCID 55271418HCID 55271418, compoundHCID 710873465-Cyclopropyl-6-cyclopropylmethoxy-pyridine-2-carboxylic acid

Product 1

HCID 71087581HCID 71087581, compound

Procedure

The title compound was synthesized in analogy to Example 1, using 5-cyclopropyl-6-cyclopropylmethyloxy-pyridine-2-carboxylic acid (Example 42a) and 1-(cyclopropylmethyl)-hydrazinecarboxylic acid 1,1-dimethylethyl ester (CAN 1314973-05-1) as starting materials; LC-MS (UV peak area/ESI) 100%, 402.2375 (M+H)+.

Sources & evidence

ORD record
ord-2103262c09c84f2f98465d3cefa18c5e
Source dataset
uspto-grants-2016_03
Patent number
US09290451B2

Reaction notes

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