5-Cyclopropyl-6-(isobutylsulfonyl)picolinic acid → HCID 71093640, compound

HRID 927832Notes

Reaction equation

HRID 927832 reaction equation
[CH:1]1([C:4]2[CH:5]=[CH:6][C:7]([C:17]([OH:19])=O)=[N:8][C:9]=2[S:10]([CH2:13][CH:14]([CH3:16])[CH3:15])(=[O:12])=[O:11])[CH2:3][CH2:2]1.[NH2:20][C:21]([CH2:28][CH3:29])([CH2:26][CH3:27])[C:22]([NH:24][CH3:25])=[O:23]>>[CH2:26]([C:21]([NH:20][C:17]([C:7]1[CH:6]=[CH:5][C:4]([CH:1]2[CH2:2][CH2:3]2)=[C:9]([S:10]([CH2:13][CH:14]([CH3:15])[CH3:16])(=[O:11])=[O:12])[N:8]=1)=[O:19])([C:22](=[O:23])[NH:24][CH3:25])[CH2:28][CH3:29])[CH3:27]

Participants

3

Reactant 2

HCID 710877315-Cyclopropyl-6-(isobutylsulfonyl)picolinic acidHCID 798103702-Amino-2-ethyl-N-methyl-butyramide

Product 1

HCID 71093640HCID 71093640, compound

Procedure

The title compound was synthesized in analogy to Example 1, using 5-cyclopropyl-6-(isobutylsulfonyl)picolinic acid (Example 351 b) and 2-amino-2-ethyl-N-methyl-butyramide (Example 70 b) as starting materials. MS (EI): m/e=410.21 [M+H]+.

Sources & evidence

ORD record
ord-142a169bc11541348a7ec3fe50b28b99
Source dataset
uspto-grants-2016_03
Patent number
US09290451B2

Reaction notes

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