HRID927943

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID21514499

Methyl 2-amino-6-hydroxybenzoate

C8H9NO3

结构：COC(=O)c1c(N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)ccc(-c2ccoc2C=O)c1OS(=O)(=O)c1ccc(C)cc1

HCID86684729

未命名化合物

PRODUCTS

生成物

结构：COC(=O)c1c(OS(=O)(=O)c2ccc(C)cc2)cccc1N(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C

HCID86713299

未命名化合物

PROCEDURE

实验过程

Prepared by proceeding in a similar manner to Intermediate 6, starting from methyl 2-amino-6-hydroxybenzoate (prepared according to Comess et al, US2004 0167128)

WORKUP

后处理

customPrepared

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-ad7cd940fccd47ff98eedf6e31853eca
来源数据集: uspto-grants-2016_03
DOI: 10.6084/m9.figshare.5104873.v1
专利: US09290472B2
来源说明: uspto-grants-2016_03

反应 SMILES

[C:1]([O:5][C:6]([N:8]([C:37]([O:39][C:40]([CH3:43])([CH3:42])[CH3:41])=[O:38])[C:9]1[C:14]([C:15]([O:17][CH3:18])=[O:16])=[C:13]([O:19][S:20]([C:23]2[CH:28]=[CH:27][C:26]([CH3:29])=[CH:25][CH:24]=2)(=[O:22])=[O:21])[C:12](C2C=COC=2C=O)=[CH:11][CH:10]=1)=[O:7])([CH3:4])([CH3:3])[CH3:2].NC1C=CC=C(O)C=1C(OC)=O>>[C:40]([O:39][C:37]([N:8]([C:6]([O:5][C:1]([CH3:4])([CH3:3])[CH3:2])=[O:7])[C:9]1[CH:10]=[CH:11][CH:12]=[C:13]([O:19][S:20]([C:23]2[CH:24]=[CH:25][C:26]([CH3:29])=[CH:27][CH:28]=2)(=[O:22])=[O:21])[C:14]=1[C:15]([O:17][CH3:18])=[O:16])=[O:38])([CH3:42])([CH3:43])[CH3:41]