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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 927997Generated: October 30, 2026

tert-Butyl (3S)-3-(iodomethyl)pyrrolidine-1-carboxylate → tert-butyl (S)-3-(3-fluorobenzyl)-pyrrolidine-1-carboxylate

https://huagongshe.com/reaction/927997

Reaction equation

Participants

RoleNameHCIDCharge
Reactanttert-Butyl (3S)-3-(iodomethyl)pyrrolidine-1-carboxylateHCID 57375933—
Reactanttert-butyl (R)-3-(3-fluorobenzyl)pyrrolidine-1-carboxylateHCID 71006943—
Producttert-butyl (S)-3-(3-fluorobenzyl)-pyrrolidine-1-carboxylateHCID 71006981—

Reaction Steps

Prepared by proceeding in a similar manner to Intermediate 99 starting with tert-butyl (S)-3-iodomethylpyrrolidine-1-carboxylate (Intermediate 118).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09290472B2
Source datasetuspto-grants-2016_03
ORD IDord-e5147fc93fef4b3b9f7c1b167b83f478
Source noteuspto-grants-2016_03