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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 927998Generated: November 2, 2026

tert-butyl (3S)-3-(hydroxymethyl)pyrrolidine-1-carboxylate → tert-Butyl (3S)-3-(iodomethyl)pyrrolidine-1-carboxylate

https://huagongshe.com/reaction/927998

Reaction equation

Participants

RoleNameHCIDCharge
Reactanttert-butyl (3S)-3-(hydroxymethyl)pyrrolidine-1-carboxylateHCID 1514341—
Reactanttert-butyl (3R)-3-(iodomethyl)pyrrolidine-1-carboxylateHCID 59371368—
Producttert-Butyl (3S)-3-(iodomethyl)pyrrolidine-1-carboxylateHCID 57375933—

Reaction Steps

Prepared by proceeding in a similar manner to Intermediate 100 starting with tert-butyl (S)-3-hydroxymethylpyrrolidine-1-carboxylate.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09290472B2
Source datasetuspto-grants-2016_03
ORD IDord-42b3103388d04855b5ca42f4ab269f73
Source noteuspto-grants-2016_03