N-((S)-1-ethylpyrrolidin-3-yl)-N-methylamine dihydrochloride → N-((R)-1-ethylpyrrolidin-3-yl)-N-methylamine dihydrochloride

HRID 928008Notes

Reaction equation

HRID 928008 reaction equation
[ClH:1].Cl.[CH2:3]([N:5]1[CH2:9][CH2:8][C@H:7]([NH:10][CH3:11])[CH2:6]1)[CH3:4].C(N1CC[C@@H](N(C)C(=O)OCC2C=CC=CC=2)C1)C>>[ClH:1].[ClH:1].[CH2:3]([N:5]1[CH2:9][CH2:8][C@@H:7]([NH:10][CH3:11])[CH2:6]1)[CH3:4]

Participants

3

Reactant 2

HCID 86713333N-((S)-1-ethylpyrrolidin-3-yl)-N-methylamine dihydrochlorideHCID 86713337benzyl N-((R)-1-ethylpyrrolidin-3-yl)-N-methylcarbamate2×

Product 1

HCID 86713336N-((R)-1-ethylpyrrolidin-3-yl)-N-methylamine dihydrochloride

Procedure

Prepared by proceeding in a similar manner to Intermediate 127, starting from benzyl N—((R)-1-ethylpyrrolidin-3-yl)-N-methylcarbamate (Intermediate 133) as a light coloured viscous oil, which was used without further characterization.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-74d3b56d67514f0fb685f0929e5dddcd
Source dataset
uspto-grants-2016_03
Patent number
US09290472B2

Reaction notes

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