(S)-2-(1-Ethylpyrrolidin-2-yl)ethanamine → (R)-2-(1-Ethylpyrrolidin-2-yl)ethanamine

HRID 928016Notes

Reaction equation

HRID 928016 reaction equation
[CH2:1]([N:3]1[CH2:7][CH2:6][CH2:5][C@H:4]1[CH2:8][CH2:9][NH2:10])[CH3:2].C(N1CCC[C@H]1CC#N)(=O)C>>[CH2:1]([N:3]1[CH2:7][CH2:6][CH2:5][C@@H:4]1[CH2:8][CH2:9][NH2:10])[CH3:2]

Participants

3

Reactant 2

HCID 14447348(S)-2-(1-Ethylpyrrolidin-2-yl)ethanamineHCID 45085914(S)-2-(1-Acetylpyrrolidin-2-yl)acetonitrile2×

Product 1

HCID 45087920(R)-2-(1-Ethylpyrrolidin-2-yl)ethanamine

Procedure

Prepared by proceeding in a similar manner to Intermediate 136, starting from ((S)-1-acetylpyrrolidin-2-yl)acetonitrile (Intermediate 142) and used without further characterisation.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-ffb799b1b03045beac6598b61d899bf1
Source dataset
uspto-grants-2016_03
Patent number
US09290472B2

Reaction notes

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