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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 928019Generated: October 30, 2026

tert-butyl (2S)-2-(cyanomethyl)pyrrolidine-1-carboxylate → tert-butyl (2R)-2-(cyanomethyl)pyrrolidine-1-carboxylate

https://huagongshe.com/reaction/928019

Reaction equation

Participants

RoleNameHCIDCharge
Reactanttert-butyl (2S)-2-(cyanomethyl)pyrrolidine-1-carboxylateHCID 10727174—
Reactant(R)-tert-Butyl 2-((tosyloxy)methyl)pyrrolidine-1-carboxylateHCID 11760051—
Producttert-butyl (2R)-2-(cyanomethyl)pyrrolidine-1-carboxylateHCID 10727173—

Reaction Steps

Prepared by proceeding in a similar manner to Intermediate 139, starting from tert-butyl (R)-2-(4-methylbenzenesulfonyloxymethyl)pyrrolidine-1-carboxylate (Intermediate 145) and used without further characterisation.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09290472B2
Source datasetuspto-grants-2016_03
ORD IDord-c921837edcd842c4908b31aea1ee259c
Source noteuspto-grants-2016_03