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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 928020Generated: October 31, 2026

N-(tert-Butoxycarbonyl)-D-prolinol → (R)-tert-Butyl 2-((tosyloxy)methyl)pyrrolidine-1-carboxylate

https://huagongshe.com/reaction/928020

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-(tert-Butoxycarbonyl)-D-prolinolHCID 688279—
Reactanttert-Butyl (2S)-2-(((4-methylbenzene-1-sulfonyl)oxy)methyl)pyrrolidine-1-carboxylateHCID 11783214—
Product(R)-tert-Butyl 2-((tosyloxy)methyl)pyrrolidine-1-carboxylateHCID 11760051—

Reaction Steps

Prepared by proceeding in a similar manner to Intermediate 140, starting from tert-butyl (R)-2-hydroxymethylpyrrolidine-1-carboxylate and used without further characterisation.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09290472B2
Source datasetuspto-grants-2016_03
ORD IDord-0bd717d5d57448e28852a497d6928ecf
Source noteuspto-grants-2016_03