(S)-1-ethylpyrrolidine-3-carboxylic acid → (R)-1-ethylpyrrolidine-3-carboxylic acid

HRID 928057Notes

Reaction equation

HRID 928057 reaction equation
[CH2:1]([N:3]1[CH2:7][CH2:6][C@H:5]([C:8]([OH:10])=[O:9])[CH2:4]1)[CH3:2].C(N1CC[C@@H](C(OCC2C=CC=CC=2)=O)C1)C>>[CH2:1]([N:3]1[CH2:7][CH2:6][C@@H:5]([C:8]([OH:10])=[O:9])[CH2:4]1)[CH3:2]

Participants

3

Reactant 2

HCID 28064096(S)-1-ethylpyrrolidine-3-carboxylic acidHCID 86713357benzyl (R)-1-ethylpyrrolidine-3-carboxylate2×

Product 1

HCID 28064094(R)-1-ethylpyrrolidine-3-carboxylic acid

Procedure

Prepared by proceeding in a similar manner to Intermediate 189, starting from benzyl (R)-1-ethylpyrrolidine-3-carboxylate (Intermediate 197).

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-7bb0b38edec34407be5ba93642012097
Source dataset
uspto-grants-2016_03
Patent number
US09290472B2

Reaction notes

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