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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 928059Generated: October 27, 2026

(3R)-1-[(tert-butoxy)carbonyl]pyrrolidine-3-carboxylic acid → (R)-tert-butyl 3-(benzyloxycarbonyl)pyrrolidine-1-carboxylate

https://huagongshe.com/reaction/928059

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(3R)-1-[(tert-butoxy)carbonyl]pyrrolidine-3-carboxylic acidHCID 1512491—
Reactantbenzyl (S)-1-tert-butoxycarbonylpyrrolidine-3-carboxylateHCID 59016658—
Product(R)-tert-butyl 3-(benzyloxycarbonyl)pyrrolidine-1-carboxylateHCID 86713359—

Reaction Steps

Prepared by proceeding in a similar manner to Intermediate 192, starting from (R)-1-tert-butoxycarbonyl-pyrrolidine-3-carboxylic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09290472B2
Source datasetuspto-grants-2016_03
ORD IDord-ff71ac901420444b825f77f9b9e4222c
Source noteuspto-grants-2016_03