tert-Butyl (3R)-3-(cyanomethyl)pyrrolidine-1-carboxylate → HCID 86713367, compound

HRID 928067Notes

Reaction equation

HRID 928067 reaction equation
[ClH:1].[NH:2]1[CH2:6][CH2:5][C@@H:4]([CH2:7][C:8]#[N:9])[CH2:3]1.C(C[C@H]1CCN(C(OC(C)(C)C)=O)C1)#N>>[ClH:1].[NH:2]1[CH2:6][CH2:5][C@H:4]([CH2:7][C:8]#[N:9])[CH2:3]1

Participants

3

Reactant 2

HCID 11769759tert-Butyl (3R)-3-(cyanomethyl)pyrrolidine-1-carboxylate2×HCID 86713362HCID 86713362, compound

Product 1

HCID 86713367HCID 86713367, compound

Procedure

Prepared by proceeding in a similar manner to Intermediate 205, starting from tert-butyl (R)-3-cyanomethylpyrrolidine-1-carboxylate (Intermediate 211) and used without further characterisation.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-f5ea411658ed40d68061f748aa637555
Source dataset
uspto-grants-2016_03
Patent number
US09290472B2

Reaction notes

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