4-Fluorobenzylamine → N-benzyl-2-(3-(2-(4-fluorobenzylamino)-2-oxoethyl)-2-oxoimidazolidin-1-yl)-4-methylthiazole-5-carboxamide

HRID 92807Notes

Reaction equation

HRID 92807 reaction equation
[CH2:27]([c:28]1[cH:29][cH:30][cH:31][cH:32][cH:33]1)[NH:34][C:35](=[O:36])[c:37]1[c:38]([CH3:52])[n:39][c:40]([N:42]2[C:43](=[O:51])[N:44]([CH2:47][C:48](=[O:49])[OH:50])[CH2:45][CH2:46]2)[s:41]1.[CH3:1][c:2]1[cH:3][c:4]([N:5]2[CH2:6][CH2:7][N:8]([CH2:9][c:10]3[cH:11][cH:12][c:13]([C:14]([F:15])([F:16])[F:17])[cH:18][cH:19]3)[C:20]2=[O:21])[s:22][c:23]1[C:24]([OH:25])=[O:26].[F:53][c:54]1[cH:55][cH:56][c:57]([CH2:58][NH2:59])[cH:60][cH:61]1>>[CH2:27]([c:28]1[cH:29][cH:30][cH:31][cH:32][cH:33]1)[NH:34][C:35](=[O:36])[c:37]1[c:38]([CH3:52])[n:39][c:40]([N:42]2[C:43](=[O:51])[N:44]([CH2:47][C:48](=[O:50])[NH:59][CH2:58][c:57]3[cH:56][cH:55][c:54]([F:53])[cH:61][cH:60]3)[CH2:45][CH2:46]2)[s:41]1

Participants

4

Reactant 3

HCID 673264-FluorobenzylamineHCID 580315813-Methyl-5-(2-oxo-3-(4-(trifluoromethyl)benzyl)imidazolidin-1-yl)thiophene-2-carboxylic acidHCID 594812672-(3-(5-(Benzylcarbamoyl)-4-methylthiazol-2-yl)-2-oxoimidazolidin-1-yl)acetic acid

Product 1

HCID 59481295N-benzyl-2-(3-(2-(4-fluorobenzylamino)-2-oxoethyl)-2-oxoimidazolidin-1-yl)-4-methylthiazole-5-carboxamide

Sources & evidence

ORD record
ord-5d87b84cf72f4127b08184b823e68ed7
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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