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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 928269Generated: October 25, 2026

3-Methyl-4-pyridinamine → 2-(5-Bromo-2-pyrrolidin-1-ylphenyl)-4-(3-methyl-4-pyridylamino)pteridine

https://huagongshe.com/reaction/928269

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Methyl-4-pyridinamineHCID 74811—
Reactant2-(5-Bromo-2-fluorophenyl)-4-(4-pyridylamino)pteridineHCID 11962218—
Reactant2-(5-Bromo-2-pyrrolidin-1-ylphenyl)pteridin-4-oneHCID 136109957—
Product2-(5-Bromo-2-pyrrolidin-1-ylphenyl)-4-(3-methyl-4-pyridylamino)pteridineHCID 57742370—

Reaction Steps

The title product was synthesized by reaction of the 2-(5-bromo-2-pyrrolidin-1-yl-phenyl)pteridin-4-one 110 and 4-amino-3-methylpyridine following the procedure described for 4-(4-pyridylamino)-2-(5-bromo-2-fluorophenyl)pteridine 1 (LCMS analysis).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09290502B2
Source datasetuspto-grants-2016_03
ORD IDord-21295f404408445a956eb92576208a57
Source noteuspto-grants-2016_03