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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 928271Generated: October 25, 2026

2-(5-Bromo-2-fluorophenyl)-4-(4-pyridylamino)pteridine → 4-[(Butyl)(4-pyridyl)amino]-2-(5-bromo-2-fluorophenyl)pteridine

https://huagongshe.com/reaction/928271

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(5-Bromo-2-fluorophenyl)-4-(4-pyridylamino)pteridineHCID 11962218—
ReactantN-Butylpyridin-4-amineHCID 14322667—
Reactant2-(5-Bromo-2-fluoro-phenyl)-3H-pteridin-4-oneHCID 136109958—
Product4-[(Butyl)(4-pyridyl)amino]-2-(5-bromo-2-fluorophenyl)pteridineHCID 44432066—

Reaction Steps

The title product was synthesized by reaction of the 2-(5-bromo-2-fluorophenyl)-pteridin-4-one 104 with 4-butylaminopyridine 113 following the procedure described for 4-(4-pyridylamino)-2-(5-bromo-2-fluorophenyl)pteridine 1 (LCMS analysis).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09290502B2
Source datasetuspto-grants-2016_03
ORD IDord-899f8447edbc4744b1725f8250143c7f
Source noteuspto-grants-2016_03