4-[(Butyl)(4-pyridyl)amino]-2-(5-bromo-2-fluorophenyl)pteridine → 2-(5-Bromo-2-fluorophenyl)-4-[(3,3-dimethylbutyl)(4-pyridyl)amino]pteridine
反応式
[Br:1][C:2]1[CH:3]=[CH:4][C:5]([F:19])=[C:6]([C:8]2[NH:17][C:16](=O)[C:15]3[C:10](=[N:11][CH:12]=[CH:13][N:14]=3)[N:9]=2)[CH:7]=1.[CH3:20][C:21]([CH3:32])([CH3:31])[CH2:22][CH2:23][NH:24][C:25]1[CH:30]=[CH:29][N:28]=[CH:27][CH:26]=1.C(N(C1C=CN=CC=1)C1C2C(=NC=CN=2)N=C(C2C=C(Br)C=CC=2F)N=1)CCC>>[Br:1][C:2]1[CH:3]=[CH:4][C:5]([F:19])=[C:6]([C:8]2[N:17]=[C:16]([N:24]([CH2:23][CH2:22][C:21]([CH3:32])([CH3:31])[CH3:20])[C:25]3[CH:30]=[CH:29][N:28]=[CH:27][CH:26]=3)[C:15]3[C:10](=[N:11][CH:12]=[CH:13][N:14]=3)[N:9]=2)[CH:7]=1参加物
4
実験手順
The title product was synthesized by reaction of the 2-(5-bromo-2-fluorophenyl)-pteridin-4-one 104 with 4-(3,3-dimethylbutylamino)pyridine following the procedure described for 4-[(butyl)(4-pyridyl)amino]-2-(5-bromo-2-fluorophenyl)pteridine 3.
出典と根拠
- ORDレコード
- ord-14f091fc7d784cfba7b4e4b98d6dcd16
- 出典データセット
- uspto-grants-2016_03
- 特許番号
- US09290502B2
反応ノート
読み込み中…