HRID928319

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID68535

2-Butynoic acid

C4H4O2

结构：Nc1nccn2c([C@@H]3CCCN3)nc(-c3ccc(C(=O)Nc4nc5c(s4)CCCC5)cc3)c12

HCID71607621

未命名化合物

2 次

PRODUCTS

生成物

结构：CC#CC(=O)N1CCC[C@H]1c1nc(-c2ccc(C(=O)Nc3nc4c(s3)CCCC4)cc2)c2c(N)nccn12

HCID86720309

未命名化合物

收率 19.2%

PROCEDURE

实验过程

This compound was prepared, in an analogous manner as described in Example 2, from (S)-4-(8-amino-3-(pyrrolidin-2-yl)imidazo[1,5-a]pyrazin-1-yl)-N-(4,5,6,7-tetrahydrobenzo[d]thiazol-2-yl)benzamide (intermediate 15) and 2-butynoic acid, to afford the title compound (7 mg, 19.2%). Data: UPLC (C) Rt: 2.41 min; m/z 526.3 (M+H)+.

WORKUP

后处理

customThis compound was prepared, in an analogous manner