HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acryloyl chloride → HCID 86720310, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acryloyl chloride | HCID 13140 | — |
| Reactant | HCID 71226346 | HCID 71226346 | — |
| Product | HCID 86720310 | HCID 86720310 | 38.4% |
Reaction Steps
This compound was prepared, in an analogous manner as described in Example 1, from (S)-4-(8-amino-3-(pyrrolidin-2-yl)imidazo[1,5-a]pyrazin-1-yl)-2-fluoro-N-(pyridin-2-yl)benzamide (intermediate 17) and acryloylchloride, to afford the title compound (13 mg, 38.4%). Data: UPLC (C) Rt: 1.67 min; m/z 472.3 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09290504B2 |
| Source dataset | uspto-grants-2016_03 |
| ORD ID | ord-7501bda83633476385de3be65344b4fb |
| Source note | uspto-grants-2016_03 |