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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 928323Generated: October 30, 2026

Acryloyl chloride → HCID 86720311, compound

https://huagongshe.com/reaction/928323

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcryloyl chlorideHCID 13140—
ReactantHCID 71226538HCID 71226538—
ProductHCID 86720311HCID 8672031135.5%

Reaction Steps

This compound was prepared, in an analogous manner as described in Example 1, from (S)-4-(8-amino-3-(pyrrolidin-2-yl)imidazo[1,5-a]pyrazin-1-yl)-2-methoxy-N-(pyridin-2-yl)benzamide (intermediate 19) and acryloylchloride, to afford the title compound (14 mg, 35.5%). Data: UPLC (C) Rt: 1.74 min; m/z 484.3 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09290504B2
Source datasetuspto-grants-2016_03
ORD IDord-5aff5434d7ac420ca884cac90b8f1716
Source noteuspto-grants-2016_03