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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 928328Generated: October 30, 2026

Acryloyl chloride → HCID 86720314, compound

https://huagongshe.com/reaction/928328

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcryloyl chlorideHCID 13140—
ReactantHCID 71226716HCID 71226716—
ProductHCID 86720314HCID 8672031410.4%

Reaction Steps

This compound was prepared, in an analogous manner as described in Example 1, from (S)-4-(8-amino-3-(piperidin-2-yl)imidazo[1,5-a]pyrazin-1-yl)-N-(4-cyanopyridin-2-yl)benzamide (intermediate 24) and acryloylchloride, to afford the title compound (4.8 mg, 10.4%). Data: UPLC(C) Rt: 2.31 min.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09290504B2
Source datasetuspto-grants-2016_03
ORD IDord-82ab9407fd944e5d88784420a725eb82
Source noteuspto-grants-2016_03