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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 928330Generated: October 31, 2026

Acryloyl chloride → HCID 86720315, compound

https://huagongshe.com/reaction/928330

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcryloyl chlorideHCID 13140—
ReactantHCID 71226446HCID 71226446—
ProductHCID 86720315HCID 8672031526.2%

Reaction Steps

This compound was prepared, in an analogous manner as described in Example 1, from (S)-4-(8-amino-3-(piperidin-2-yl)imidazo[1,5-a]pyrazin-1-yl)-N-(pyrimidin-2-yl)benzamide (intermediate 27) and acryloylchloride, to afford the title compound (5.9 mg, 26.2%). Data: UPLC(C) Rt: 1.70 min; m/z 469.3 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09290504B2
Source datasetuspto-grants-2016_03
ORD IDord-bcf2883b59e84b06b7f23bfedb1f85d7
Source noteuspto-grants-2016_03