HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acryloyl chloride → HCID 86720316, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acryloyl chloride | HCID 13140 | — |
| Reactant | HCID 71226005 | HCID 71226005 | — |
| Product | HCID 86720316 | HCID 86720316 | 27.4% |
Reaction Steps
This compound was prepared, in an analogous manner as described in Example 1, from (S)-4-(8-amino-3-(piperidin-2-yl)imidazo[1,5-a]pyrazin-1-yl)-N-(4-methylpyrimidin-2-yl)benzamide (intermediate 29) and acryloylchloride, to afford the title compound (4.5 mg, 27.4%). Data: UPLC(C) Rt: 1.79 min; m/z 483.3 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09290504B2 |
| Source dataset | uspto-grants-2016_03 |
| ORD ID | ord-c8433629019c4073a6c1a52d4ea9401f |
| Source note | uspto-grants-2016_03 |