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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 928331Generated: October 28, 2026

Acryloyl chloride → HCID 86720316, compound

https://huagongshe.com/reaction/928331

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcryloyl chlorideHCID 13140—
ReactantHCID 71226005HCID 71226005—
ProductHCID 86720316HCID 8672031627.4%

Reaction Steps

This compound was prepared, in an analogous manner as described in Example 1, from (S)-4-(8-amino-3-(piperidin-2-yl)imidazo[1,5-a]pyrazin-1-yl)-N-(4-methylpyrimidin-2-yl)benzamide (intermediate 29) and acryloylchloride, to afford the title compound (4.5 mg, 27.4%). Data: UPLC(C) Rt: 1.79 min; m/z 483.3 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09290504B2
Source datasetuspto-grants-2016_03
ORD IDord-c8433629019c4073a6c1a52d4ea9401f
Source noteuspto-grants-2016_03