Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 928332Generated: October 31, 2026

2-Butynoic acid → HCID 71226670, compound

https://huagongshe.com/reaction/928332

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Butynoic acidHCID 68535—
ReactantHCID 71226466HCID 71226466—
ProductHCID 71226670HCID 7122667026.9%

Reaction Steps

This compound was prepared, in an analogous manner as described in Example 2, from (S)-4-(8-amino-3-(piperidin-2-yl)imidazo[1,5-a]pyrazin-1-yl)-N-(pyrimidin-4-yl)benzamide (intermediate 31) and 2-butynoic acid, to afford the title compound (10.3 mg, 26.9%). Data: UPLC(C) Rt: 1.91 min; m/z 481.3 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09290504B2
Source datasetuspto-grants-2016_03
ORD IDord-226bfce3c1044ee9b5e0bf7a24889804
Source noteuspto-grants-2016_03