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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 928333Generated: October 31, 2026

2-Butynoic acid → HCID 71225944, compound

https://huagongshe.com/reaction/928333

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Butynoic acidHCID 68535—
ReactantHCID 71226578HCID 71226578—
ProductHCID 71225944HCID 7122594431.8%

Reaction Steps

This compound was prepared, in an analogous manner as described in Example 2, from (S)-4-(8-amino-3-(piperidin-2-yl)imidazo[1,5-a]pyrazin-1-yl)-N-(pyridazin-3-yl)benzamide (intermediate 33) and 2-butynoic acid, to afford the title compound (11 mg, 31.8%). Data: UPLC(C) Rt: 1.92 min; m/z 481.3 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09290504B2
Source datasetuspto-grants-2016_03
ORD IDord-768562337a0a4788985fa9e497584f7f
Source noteuspto-grants-2016_03