HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
4-Propylpyridin-2-amine → 2-fluoro-N-(4-propylpyridin-2-yl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 4-Propylpyridin-2-amine | HCID 7022594 | — |
| Edukt | 4-Carboxy-3-fluorobenzeneboronic acid pinacol ester | HCID 44717665 | — |
| Edukt | N-(4-fluoropyridin-2-yl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide | HCID 71222688 | — |
| Produkt | 2-fluoro-N-(4-propylpyridin-2-yl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide | HCID 71223194 | 63,3% |
Reaktionsschritte
This compound was prepared, in an analogous manner as described in Intermediate 4, starting from commercially available 2-fluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoic acid and 4-propyl-pyridin-2-ylamine, to afford the title compound (830 mg, 63.3%).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US09290504B2 |
| Quelldatensatz | uspto-grants-2016_03 |
| ORD ID | ord-1a2d0a1923ff4ca4bfa71377ad4eb48b |
| Quellennotiz | uspto-grants-2016_03 |