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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 928339Generated: October 30, 2026

2-Butynoic acid → HCID 71226747, compound

https://huagongshe.com/reaction/928339

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Butynoic acidHCID 68535—
ReactantHCID 71225934HCID 71225934—
ProductHCID 71226747HCID 7122674759.1%

Reaction Steps

This compound was prepared, in an analogous manner as described in Example 2, from 4-(8-amino-3-((S)-piperidin-2-yl)imidazo[1,5-a]pyrazin-1-yl)-3-methyl-N-(pyridin-2-yl)benzamide (intermediate 43) and 2-butynoic acid, to afford the title compound (13.7 mg, 59.1%). Data: UPLC(C) Rt: 2.28 min; m/z 494.3 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09290504B2
Source datasetuspto-grants-2016_03
ORD IDord-01b3248d83794ea2898300822da9cf7d
Source noteuspto-grants-2016_03