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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 928350Generated: November 1, 2026

2-Butynoic acid → HCID 71226641, compound

https://huagongshe.com/reaction/928350

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Butynoic acidHCID 68535—
ReactantHCID 86720324HCID 86720324—
ProductHCID 71226641HCID 7122664133.4%

Reaction Steps

This compound was prepared, in an analogous manner as described in Example 2, from (S)-4-(8-amino-3-(1-(methylamino)ethyl)imidazo[1,5-a]pyrazin-1-yl)-N-(4-(trifluoromethyl)pyridin-2-yl)benzamide (intermediate 48) and 2-butynoic acid, to afford the title compound (11.5 mg, 33.4%). Data: UPLC(C) Rt: 2.54 min; m/z 522.2 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09290504B2
Source datasetuspto-grants-2016_03
ORD IDord-c15a9ad80dc24d5788c7eb040db5fb14
Source noteuspto-grants-2016_03