Pyrazole → HCID 58081197, compound

Participants

Reaction Steps

A suspension of methyl 4-(bromomethyl)-3-methoxybenzoate (400 mg, 1.544 mmol) and 1H-pyrazole (105 mg, 1.544 mmol) and K2CO3 (533 mg, 3.86 mmol) in DMF (5 ml) was stirred for 3.5 h at rt. A saturated solution of NaHCO3 was added and the mixture was extracted with ethyl acetate. The combined organic extracts were dried over Na2SO4, filtered and concentrated under reduced pressure to afford crude Methyl 4-((1H-pyrazol-1-yl)methyl)-3-methoxybenzoate. MS [M+H]+=247.

Provenance & Evidence