HCID 66723566, compound → HCID 56836060, compound

HRID 928459Notes

Reaction equation

HRID 928459 reaction equation
[CH3:1][C:2]1[CH:11]=[CH:10][C:9]2[C:4](=[CH:5][CH:6]=[C:7]([CH2:12][N:13]3[CH:17]=[C:16]([C:18]([OH:20])=O)[N:15]=[N:14]3)[CH:8]=2)[N:3]=1.[NH2:21][CH2:22][C:23]1[C:24]([Cl:31])=[CH:25][C:26]([NH2:30])=[N:27][C:28]=1[CH3:29]>>[NH2:30][C:26]1[N:27]=[C:28]([CH3:29])[C:23]([CH2:22][NH:21][C:18]([C:16]2[N:15]=[N:14][N:13]([CH2:12][C:7]3[CH:8]=[C:9]4[C:4](=[CH:5][CH:6]=3)[N:3]=[C:2]([CH3:1])[CH:11]=[CH:10]4)[CH:17]=2)=[O:20])=[C:24]([Cl:31])[CH:25]=1

Participants

3

Reactant 2

HCID 66723566HCID 66723566, compoundHCID 66723713HCID 66723713, compound

Product 1

HCID 56836060HCID 56836060, compound

Procedure

The title compound was prepared from 1-((2-Methylquinolin-6-yl)methyl)-1H-1,2,3-triazole-4-carboxylic acid and 5-(aminomethyl)-4-chloro-6-methylpyridin-2-amine in analogy to Example 20c). HPLC-MS (Method F) Rt=0.44 min. [M+H]+=422.1.

Sources & evidence

ORD record
ord-fbfc1f37e0cb4efa8be00233264ca8ef
Source dataset
uspto-grants-2016_03
Patent number
US09290485B2

Reaction notes

Loading…