HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → 2-Chloro-6-methylbenzoyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | Oxalyl chloride | HCID 65578 | — |
| Reactant | 2-Chloro-6-methylbenzoic acid | HCID 88870 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 2-Chloro-6-methylbenzoyl chloride | HCID 22382040 | — |
Reaction Steps
In one embodiment, the step comprises combining 2-chloro-6-methylbenzoic acid with, e.g., thionyl chloride or oxalyl chloride, optionally in the presence of a catalytic amount of DMF, to afford 2-chloro-6-methylbenzoyl chloride.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09290497B2 |
| Source dataset | uspto-grants-2016_03 |
| ORD ID | ord-9a7d3ff10c8e4dc99889dcfb35198025 |
| Source note | uspto-grants-2016_03 |