Aniline → HCID 58009020, compound

HRID 928535Notes

Reaction equation

HRID 928535 reaction equation
[Cl:1][C:2]1[CH:10]=[CH:9][CH:8]=[C:7]([CH3:11])[C:3]=1[C:4](Cl)=[O:5].[NH2:12][C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1>>[Cl:1][C:2]1[CH:10]=[CH:9][CH:8]=[C:7]([CH3:11])[C:3]=1[C:4]([NH:12][C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1)=[O:5]

Participants

3

Reactant 2

HCID 6115AnilineHCID 223820402-Chloro-6-methylbenzoyl chloride

Product 1

HCID 58009020HCID 58009020, compound

Procedure

In one embodiment, the step comprises combining 2-chloro-6-methylbenzoyl chloride with aniline to afford 2-chloro-6-methyl-N-phenylbenzamide. In one embodiment, the step is optionally carried out in the presence of a base (e.g., an amine base such as Et3N).

Sources & evidence

ORD record
ord-44f3f7a8868544a1895ab104e847f729
Source dataset
uspto-grants-2016_03
Patent number
US09290497B2

Reaction notes

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