Bromoacetone → HCID 90384266, compound

HRID 928652Notes

Reaction equation

HRID 928652 reaction equation
[Br:1][C:2]1[CH:7]=[C:6]([F:8])[C:5]([F:9])=[CH:4][C:3]=1[OH:10].Br[CH2:12][C:13](=O)[CH3:14]>>[Br:1][C:2]1[C:3]2[O:10][CH:12]=[C:13]([CH3:14])[C:4]=2[C:5]([F:9])=[C:6]([F:8])[CH:7]=1

Participants

3

Reactant 2

HCID 11715BromoacetoneHCID 27362882-Bromo-4,5-difluorophenol

Product 1

HCID 90384266HCID 90384266, compoundYield 12%

Procedure

An operation similar to that in Step 1 of Example 12 was performed using 2-bromo-4,5-difluorophenol (1.05 g, 5.00 mmol) in place of 2-bromo-4-fluorophenol, and bromoacetone (0.504 mL, 6.00 mmol) in place of bromoacetaldehyde dimethyl acetal to thus obtain the title compound.

Sources & evidence

ORD record
ord-3beb23374acb4ea4ac23a5050bdef0d3
Source dataset
uspto-grants-2016_03
Patent number
US09290487B2

Reaction notes

Loading…