5-(4-Methoxybenzyl)-2,2-dimethyl-1,3-dioxane-4,6-dione → 2-(4-Methoxybenzyl)Malonic Acid

HRID 928724ノート

反応式

HRID 928724 の反応式
ClC1C=CC(CC2C(=O)OC(C)(C)OC2=O)=CC=1.BrC1C=C2C(=CC=1)N=C(Cl)C(CC1C=CC(Cl)=CC=1)=C2Cl.[CH3:40][O:41][C:42]1[CH:58]=[CH:57][C:45]([CH2:46][CH:47]2[C:52](=[O:53])[O:51]C(C)(C)[O:49][C:48]2=[O:56])=[CH:44][CH:43]=1>>[CH3:40][O:41][C:42]1[CH:43]=[CH:44][C:45]([CH2:46][CH:47]([C:48]([OH:56])=[O:49])[C:52]([OH:53])=[O:51])=[CH:57][CH:58]=1

参加物

4

反応物 3

HCID 6655385-(4-Methoxybenzyl)-2,2-dimethyl-1,3-dioxane-4,6-dioneHCID 108801105-(4-Chlorobenzyl)-2,2-dimethyl-1,3-dioxane-4,6-dioneHCID 867155806-Bromo-2,4-dichloro-3-(4-chlorobenzyl)quinoline3 回

生成物 1

HCID 143920722-(4-Methoxybenzyl)Malonic Acid

実験手順

The title compound was prepared by substituting 5-(4-chlorobenzyl)-2,2-dimethyl-1,3-dioxane-4,6-dione (Intermediate 3: step a) with 5-(4-methoxybenzyl)-2,2-dimethyl-1,3-dioxane-4,6-dione (Intermediate 7: step a) then following the procedure described for the preparation of 2-(4-chlorobenzyl)malonic acid (Intermediate 3: step b).

出典と根拠

ORDレコード
ord-40f91aeefd8246b48131862d1eff4b9a
出典データセット
uspto-grants-2016_03
特許番号
US09290476B2

反応ノート

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