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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 928728Generated: October 31, 2026

6-Bromo-2,4-dichloro-3-(4-chlorobenzyl)quinoline → 6-Bromo-2,4-dichloro-3-(4-(methylsulfonyl)benzyl)quinoline

https://huagongshe.com/reaction/928728

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-Bromo-2,4-dichloro-3-(4-chlorobenzyl)quinolineHCID 86715580—
Reactant2-(4-Methylsulfonylbenzyl)malonic acidHCID 86715586—
Product6-Bromo-2,4-dichloro-3-(4-(methylsulfonyl)benzyl)quinolineHCID 86715587—

Reaction Steps

The title compound was prepared by substituting 2-(4-chlorobenzyl)malonic acid (Intermediate 3: step b) with 2-(4-methylsulfonylbenzyl)malonic acid (Intermediate 8: step b) then following the procedure described for the preparation of 6-bromo-2,4-dichloro-3-(4-chlorobenzyl)quinoline (Intermediate 3: step c).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09290476B2
Source datasetuspto-grants-2016_03
ORD IDord-3b06a96b2d824b21be24dae7ad15765b
Source noteuspto-grants-2016_03