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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 928746Generated: October 25, 2026

N-methoxy-N-methyl-4-nitrobenzamide → (1-Methyl-1H-imidazol-5-yl)(4-nitrophenyl)methanone

https://huagongshe.com/reaction/928746

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-methoxy-N-methyl-4-nitrobenzamideHCID 2991007—
ReactantN-Methoxy-N-methyl-1,3-thiazole-5-carboxamideHCID 25307138—
Reactant(1-Methyl-1H-imidazol-5-yl)(thiazol-5-yl)methanoneHCID 86715592—
Product(1-Methyl-1H-imidazol-5-yl)(4-nitrophenyl)methanoneHCID 86715600—

Reaction Steps

The title compound was prepared by substituting N-methoxy-N-methylthiazole-5-carboxamide (Intermediate 11: step a) with N-methoxy-N-methyl-4-nitrobenzamide (Intermediate 20: step a) then following the procedure described for the preparation of (1-methyl-1H-imidazol-5-yl)(thiazol-5-yl)methanone (Intermediate 13).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09290476B2
Source datasetuspto-grants-2016_03
ORD IDord-e4a3596e0f244584b74197e096f27796
Source noteuspto-grants-2016_03