HCID 66117559, compound → (4-Fluorophenyl)(1-methyl-1H-imidazol-5-yl)methanone

HRID 928760Notes

Reaction equation

HRID 928760 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][C:5]([CH:8]([C:10]2[N:14]([CH3:15])[CH:13]=[N:12][CH:11]=2)[OH:9])=[CH:4][CH:3]=1.CN1C(C(C2C=CC=CN=2)O)=CN=C1>>[F:1][C:2]1[CH:3]=[CH:4][C:5]([C:8]([C:10]2[N:14]([CH3:15])[CH:13]=[N:12][CH:11]=2)=[O:9])=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 66117559HCID 66117559, compoundHCID 86715604(1-Methyl-1H-imidazol-5-yl)(pyridin-2-yl)methanol

Product 1

HCID 71711558(4-Fluorophenyl)(1-methyl-1H-imidazol-5-yl)methanone

Procedure

The title compound was prepared analogously to the method in Intermediate 25: step b using (4-fluorophenyl)(1-methyl-1H-imidazol-5-yl)methanol (Intermediate 29: step a) in place of (1-methyl-1H-imidazol-5-yl)(pyridin-2-yl)methanol.

Sources & evidence

ORD record
ord-1c4a79a660c44143a0ef2b944342a07f
Source dataset
uspto-grants-2016_03
Patent number
US09290476B2

Reaction notes

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