(3-Fluorophenyl)(pyridin-3-yl)methanol → 3-(3-Fluorobenzoyl)pyridine

HRID 928762Notes

Reaction equation

HRID 928762 reaction equation
[F:1][C:2]1[CH:3]=[C:4]([CH:8]([C:10]2[CH:11]=[N:12][CH:13]=[CH:14][CH:15]=2)[OH:9])[CH:5]=[CH:6][CH:7]=1.CN1C(C(C2C=CC=CN=2)O)=CN=C1>>[F:1][C:2]1[CH:3]=[C:4]([C:8]([C:10]2[CH:11]=[N:12][CH:13]=[CH:14][CH:15]=2)=[O:9])[CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 13285820(3-Fluorophenyl)(pyridin-3-yl)methanolHCID 86715604(1-Methyl-1H-imidazol-5-yl)(pyridin-2-yl)methanol

Product 1

HCID 129300293-(3-Fluorobenzoyl)pyridine

Procedure

The title compound was prepared analogously to the method in Intermediate 25: step b using (3-fluorophenyl)(pyridin-3-yl)methanol (Intermediate 32: step a) in place of (1-methyl-1H-imidazol-5-yl)(pyridin-2-yl)methanol.

Sources & evidence

ORD record
ord-7681c76a0d704395bde69d2b6a834b15
Source dataset
uspto-grants-2016_03
Patent number
US09290476B2

Reaction notes

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