HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → 6-Chloronicotinoyl Chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 6-Chloronicotinic acid | HCID 79222 | — |
| Product | 6-Chloronicotinoyl Chloride | HCID 2782165 | — |
Reaction Steps
Into a 250-mL round-bottom flask was placed a solution of 6-chloropyridine-3-carboxylic acid (15.8 g, 100.28 mmol) in thionyl chloride (100 mL). The resulting solution was heated to reflux for 5 hours. The resulting mixture was concentrated under vacuum to give the title compound as yellow oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09290476B2 |
| Source dataset | uspto-grants-2016_03 |
| ORD ID | ord-fb1aa8b8fc134b1286662d94da068683 |
| Source note | uspto-grants-2016_03 |